Why We Invested In Plenful

I'm thrilled to announce Notable Capital's Series B investment in Plenful, the AI workflow automation platform transforming pharmacy and healthcare operations.

Everyone has a story about the healthcare system – whether it’s a moment of incredible care or deep frustration. But behind every patient experience is an invisible engine: the operational backbone that keeps things moving. And too often, that engine is powered by manual workflows. Healthcare teams are drowning in administrative work. Pharmacy technicians are spending hours on spreadsheets and data entry instead of prioritizing high-value work that delivers a better patient care experience. It’s a trillion-dollar challenge hiding in plain sight. And beyond the high cost, these challenges also burn out healthcare workers, introduce human error, and in some cases, delay patient care. 

Plenful is tackling this problem from the inside out.

Plenful is a workflow automation platform that tackles the operational complexity in healthcare—starting with pharmacy, but with this funding round, is quickly expanding across new verticals and introducing new use cases. From 340B audits to prior authorization workflows, Plenful helps healthcare staff reclaim their time and focus on higher-impact work. By automating the repetitive and error-prone tasks that bog down operations, the platform delivers immediate, measurable ROI: up to 95% time savings for healthcare teams, and dramatic improvements in compliance and reporting accuracy by running a 100%, continuous audit of claims.

In just a few years, Plenful has grown to support over 60 leading healthcare organizations, including Medical University of South Carolina (MUSC), Cencora, Renown Health, Shields Healthcare Group, Samaritan Health, and more. In the ever-evolving healthcare AI landscape, Plenful stood out to us by focusing on real value and outcomes.

The moment I met Founder & CEO Joy Liu, I knew she was building from a place of deep conviction and first-hand experience. Joy began her career at Goldman Sachs, but it was her experience as a patient advocate for a family member that exposed her to the complex infrastructure behind healthcare delivery. That experience opened her eyes to the inefficiencies and fragility of our healthcare system and launched her journey into healthcare operations. She went on to work at Shields Health Solutions, a leader in specialty pharmacy operations, where she worked alongside pharmacists, technicians, and 340B teams to serve patients and saw the broken workflows firsthand. 

What makes Joy exceptional isn’t just her domain knowledge. It’s her ability to lead with clarity, precision, and care. She’s built a world-class team of operators, engineers, product, and customer leaders who share her urgency and her belief that fixing healthcare starts with empowering the people on the ground. Her unique blend of operational experience and personal empathy is what makes Joy the perfect leader for Plenful.

We’re so proud to support Plenful’s Series B and to welcome Mitchell Rales, co-founder of Danaher, to the board. At Notable Capital, we believe in backing category-defining founders who are building the infrastructure of the future. Joy and the Plenful team are doing just that—bringing modern, intelligent software to one of the most overburdened and under-innovated parts of our healthcare system.